Red Blood Cell Biology Laboratory

A. Relevant publications

Red Cell biology in health and disease - RBC as biomarker of systemic states

1. The frequency of the allele αLELY, a low expression allele of the gene encoding erythroid spectrin α-chain, in the Greek population. Haematologica, 1999. https://pubmed.ncbi.nlm.nih.gov/10457417/
2. A novel case of a haemoglobin H disease associated with clinical and morphological characteristics of congenital dyserythropoetic anaemia type I. Eur J Haematol, 68(4): 247-252, 2002. https://doi.org/10.1034/j.1600-0609.2002.01590.x
3. Ultrastructural characterization of the erythroid cells in a novel case of congenital anaemia. Blood Cells Mol Dis, 2003. https://doi.org/10.1016/S1079-9796(03)00006-8
4. Defective organization of the erythroid cell membrane in a novel case of congenital anemia. Blood Cells Mol Dis, 2003. https://doi.org/10.1016/S1079-9796(03)00007-X
5. Physiologically important secondary modifications of red cell membrane in hereditary spherocytosis-evidence for in vivo oxidation and lipid rafts protein variations. Blood Cells Mol Dis, 2007. https://doi.org/10.1016/j.bcmd.2006.10.163
6. Structural alterations of the erythrocyte membrane proteins in diabetic retinopathy. Graefe’s Arch Clin Exp Ophthalmol, 2007. https://doi.org/10.1007/s00417-006-0500-6
7. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res, 2009. https://doi.org/10.1158/1078-0432.CCR-08-1805
8. Increased protein carbonylation of red blood cell membrane in diabetic retinopathy. Exp Mol Pathol, 2009. https://doi.org/10.1016/j.yexmp.2009.04.001
9. Aging and death signaling in mature red cells: from basic science to transfusion practice. Blood Transfus, 2010. https://doi.org/10.2450/2010.007S
10. Oxidative stress-associated shape transformation and membrane proteome remodeling in erythrocytes of end stage renal disease patients on hemodialysis. J Proteomics, 2011. https://doi.org/10.1016/j.jprot.2011.04.009
11. Apolipoprotein J/Clusterin is a novel structural component of human erythrocytes and a biomarker of cellular stress and senescence. PLoS ONE, 2011. https://doi.org/10.1371/journal.pone.0026032
12. Blood modifications associated with end stage renal disease duration, progression and cardiovascular mortality: a 3-year follow-up pilot study. J Proteomics, 2014. https://doi.org/10.1016/j.jprot.2014.02.009
13. Red blood cell abnormalities and the pathogenesis of anemia in end stage renal disease. Proteomics Clin Appl, 2016. https://doi.org/10.1002/prca.201500127
14. Pathophysiological aspects of red blood cells in end-stage renal disease patients resistant to recombinant human erythropoietin therapy. Eur J Haematol, 2017. https://doi.org/10.1111/ejh.12875
15. Short-term effects of hemodiafiltration versus conventional hemodialysis on erythrocyte performance. Can J Physiol Pharmacol, 2018. https://doi.org/10.1139/cjpp-2017-0285
16. Coagulation abnormalities in renal pathology of chronic kidney disease: the interplay between blood cells and soluble factors. Biomolecules, 2021. https://doi.org/10.3390/biom11091309
17. In Sickness and in Health: Erythrocyte Responses to Stress and Aging. Int J Mol Sci 2022. https://doi.org/10.3390/ijms23136957